Aseptic Filling Machines for Four Barrels

2025-05-22 14:31:05 glzon

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Aseptic Filling Machines for Four Barrels: Flexible, High-Speed, and Contamination-Free Solution


Overview

The Aseptic Filling Machine for Four Barrels is designed to handle the aseptic filling of liquids (e.g., pharmaceuticals, dairy, beverages, cosmetics) into pre-sterilized containers or barrier systems. With a capacity to manage up to four barrels simultaneously, it ensures high throughput, sterility, and product integrity. Ideal for small to medium-scale production, it integrates advanced aseptic technology with user-friendly automation.


Key Features

Aseptic Safety & Compliance

  • Isolator Technology: Enclosed fill zone with HEPA/ULPA filtration to maintain ISO 5 cleanroom conditions.

  • SIP/CIP Capability: Steam-in-place (SIP) and clean-in-place (CIP) systems for automated sterilization of pipes, hoses, and nozzles.

  • Barrier System Compatibility: Supports pre-sterilized containers (e.g., bottles, pouches, vials) or integrated barrier packaging (e.g., Form-Fill-Seal).

  • GMP Compliance: Meets FDA, EMA, and ISO 14644-1 standards for aseptic processes.

Four-Barrel Efficiency

  • Multi-Product Handling: Simultaneously fill products from up to four different barrels (e.g., different formulations or batches).

  • Rapid Changeover: Quick-swap manifolds and programmable HMI for seamless transitions between products.

  • Precision Fill Weight: High-accuracy weighing modules (±0.1–0.5% error) for consistent fill levels.

High-Speed & Versatility

  • Adjustable Throughput: Up to 1,200 bottles/hour (dependent on container size and product viscosity).

  • Container Flexibility: Suitable for glass/plastic bottles, vials, pouches, and syringes (e.g., 5mL–1L).

  • Capping & Sealing: Optional integration with crimpers, cappers, or ultrasonic sealers for hermetic closures.

Automation & Usability

  • Touchscreen HMI: Intuitive interface for recipe storage, batch logging, and real-time monitoring.

  • Servo-Driven Indexing: Precise container handling and positioning under fill heads.

  • Remote Access: Ethernet/IoT connectivity for data logging, OEE tracking, and predictive maintenance alerts.

Material & Product Compatibility

  • Chemical Resistance: Stainless steel (316L) construction with optional Hastelloy or PTFE coatings for corrosive products.

  • Temperature Control: Heated hoppers or inline heaters for viscous products (e.g., creams, suspensions).

  • Vacuum Support: Nitrogen purging or vacuum filling to prevent foaming and oxidation.


Applications

  • Pharmaceuticals: Sterile injectables, oral liquids, ophthalmic solutions, and biotech products.

  • Food & Beverage: Aseptic dairy, juices, sauces, and ready-to-eat meals in pouches.

  • Cosmetics: Serums, creams, toners, and other preservative-free formulations.

  • Chemicals: Specialty solvents, adhesives, and industrial fluids requiring aseptic handling.


Optional Enhancements

  • Vision Systems: AI-powered camera inspection for defect detection (e.g., cap alignment, fill level).

  • Data Integration: MES/SAP connectivity for traceability (batch numbers, expiration dates, serialization).

  • Robotic Handling: Automated loading/unloading with collaborative robots (e.g., for trays or nests).

  • Form-Fill-Seal (FFS): Inline thermoforming for blister packs or stand-up pouches.


Benefits

  1. Aseptic Guarantee: Eliminates post-fill sterilization needs, reducing product contamination risks.

  2. Multi-Product Agility: Four independent barrels enable flexible production without cross-contamination.

  3. Speed & Precision: High throughput with ±0.1% fill accuracy, minimizing giveaway and rework.

  4. Regulatory Readiness: Full audit trails, validation support, and compliance with global standards.

  5. Low Maintenance: SIP/CIP reduces manual cleaning effort and ensures repeatability.


Why Choose This Machine?

This aseptic filling machine combines four-barrel flexibility, high-speed automation, and contamination-free precision to streamline aseptic production. Its modular design, compliance with GMP/ISO standards, and scalability make it ideal for industries requiring strict sterility and efficient multi-product workflows.


Ready to ensure sterile, efficient filling? Contact us for a customized solution and demo!

Immediate Order:

Website: https://www.glzon.com/product/drumfillingmachines-en.html

Alibaba: https://www.alibaba.com/product-detail/High-Speed-Drum-Filling-Machine-Automatic_1601405682760.html?spm=a2747.product_manager.0.0.515e2c3cjNCu3K

China Manufacturing Co Ltd.: https://fillingmachinecn.en.made-in-china.com

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